{"id":326,"date":"2021-04-30T00:30:37","date_gmt":"2021-04-30T00:30:37","guid":{"rendered":"https:\/\/medizoop.com\/in\/whooping-cough-and-croup-bordetella-pertussis-h-influenza-and-parainfluenza\/"},"modified":"2021-04-30T00:30:37","modified_gmt":"2021-04-30T00:30:37","slug":"whooping-cough-and-croup-bordetella-pertussis-h-influenza-and-parainfluenza","status":"publish","type":"post","link":"https:\/\/medizoop.com\/in\/whooping-cough-and-croup-bordetella-pertussis-h-influenza-and-parainfluenza\/","title":{"rendered":"Whooping Cough and Croup &#8211; Bordetella Pertussis, H. Influenza, and Parainfluenza"},"content":{"rendered":"<p><iframe loading=\"lazy\"  width=\"580\" height=\"385\" src=\"https:\/\/www.youtube.com\/embed\/9-88zL8zWvk?rel=0&#038;cc_load_policy=1&#038;hl=en\" frameborder=\"0\" allowfullscreen><\/iframe><br \/>\nStudies on the activities of various B. pertussis virulence factors include the immunomodulatory activities of filamentous hemagglutinin, fimbriae, and adenylate cyclase toxin. Recently emerging B. pertussis strains show evidence of genetic selection for vaccine escape mutants, with changes in vaccine antigen-expressing genes, some of which may have increased the virulence of this pathogen. Severe and fatal pertussis in young infants continues to be a problem, with several studies highlighting predictors of fatality, including the extreme leukocytosis associated with this infection. Treatments for pertussis are extremely limited, though early antibiotic intervention may be beneficial. Neutralizing pertussis toxin activity may be an effective strategy, as well as targeting two host proteins, pendrin and sphingosine-1-phosphate receptors, as novel potential therapeutic interventions. (See citation below)<\/p>\n<p>Pocket Apps<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\n\ud83e\ude78 Pocket ECG<\/p>\n<p>\ud83c\udfe5 Pocket Guidelines<\/p>\n<p>\u2764\ufe0f Pocket Heart Sounds<\/p>\n<p>\ud83e\ude7a Pocket Lung Sounds<\/p>\n<p>\ud83d\udc8a Pocket Labs<\/p>\n<p>\ud83e\udda0 Pocket Micro<\/p>\n<p>\ud83e\udd7c Pocket OSCE<\/p>\n<p>Topic References<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\n\ud83c\udf0e<br \/>\n\ud83c\udf0e<br \/>\n\ud83c\udf0e<\/p>\n<p>Description&#8217;s Citation<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nCarbonetti NH. Bordetella pertussis: new concepts in pathogenesis and treatment. Curr Opin Infect Dis. 2016;29(3):287-294. doi:10.1097\/QCO.0000000000000264<\/p>\n<p>Music Credit<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nTitle: Ticker by Silent Partner<br \/>\nTitle: Always Dreaming by Within Reach<br \/>\nTitle: Drift by Drift<\/p>\n<p>Software and Hardware<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nMicrophone: Blue Yeti X Professional Condenser<br \/>\nAudio Software: Adobe Audition CC 2020<br \/>\nVideo Software: Filmora-X and Adobe After Effects CS 6<br \/>\nThumbnail Software: Adobe Photoshop CS 6<\/p>\n<p>Join Us<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nInstagram<\/p>\n<p>Twitter<\/p>\n<p>Whatsapp Study Group<\/p>\n<p>Thanks for watching. You are awesome!<br \/>\n<br \/><a href=\"https:\/\/www.youtube.com\/watch?v=9-88zL8zWvk\">source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Studies on the activities of various B. pertussis virulence factors include the immunomodulatory activities of filamentous hemagglutinin, fimbriae, and adenylate cyclase toxin. Recently emerging B. pertussis strains show evidence of genetic selection for vaccine escape mutants, with changes in vaccine antigen-expressing genes, some of which may have increased the virulence of this pathogen. Severe and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":327,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"_links":{"self":[{"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/posts\/326"}],"collection":[{"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/comments?post=326"}],"version-history":[{"count":0,"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/posts\/326\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/media\/327"}],"wp:attachment":[{"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/media?parent=326"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/categories?post=326"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medizoop.com\/in\/wp-json\/wp\/v2\/tags?post=326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}